Traditional Stainless Steel Seed Train

How are biopharmaceutical manufacturers incorporating connectors into their traditional stainless steel seed train?

• Scaling up inoculum is accomplished by using a dedicated series of stainless steel bioreactors linked together with valves and rigid tubing.
• To prevent contamination between production runs, a CIP system is designed into each bioreactor, vessel and piping line to remove any residual materials.
• Sterility assurance at the start of each culture is provided by a SIP system consisting of steam pipes, temperature sensors, and condensate collection piping.
  

Single-Use Bioreactor Feeding Stainless Steel Seed Train
Single-Use Seed Train