Steam-In-Place (SIP)
One of the most common methods for creating a sterile bioprocessing environment is the use of heat in the form of steam to eliminate unwanted organisms. Autoclaving is often impractical for large bioprocess equipment. Steam-In-Place (SIP) is an alternative sterilization method and involves sterilizing by means of steam the interior of pipes, vessels, process equipment, and associated fittings, without disassembly.
To see how steam can be used as a sterilization method, view
Steam-Thru® connection movie
Steam-Thru II connection movie
Back to Sterilization through Steam-In-Place (SIP)